Condition that affects premature infants related to a
deficiency of surface active agent surfactant.
Infants are symptomatic immediately or soon after birth.
X-ray - diffuse reticulogranular or ground glass appearance to
lungs due to microatelectasis. Air
bronchogram seen at lung bases. Pulmonary interstitial
emphysema may develop with therapy.
Complications - pneumothorax, bronchopulmonary dysplasia,
persistent patent ductus with CHF.
Neonatal pneumonia
Occurs because of interuterine infection (i.e. cytomegalic
inclusion virus) or shortly after birth.
Virus can be principle cause although other organism such as
strep, staph or E Coli. Common viral pneumonias include
H. flu and herpes.
X-ray - patchy infiltrate in perihilar area. May lead to diffuse
involvement of entire lungs. Occasionally pleural
effusion may occur.
Complications - generalized sepsis or lung abscess may occur.
Therapy - appropriate antibiotic along with oxygen and fluid
support as needed.
Tuberculosis
May occur in newborns because of interuterine infection or may
be acquired in infancy.
Infants may not appear to have clinical disease despite postive
cultures.
X-ray - frequently shows adenopathy with peripheral patchy
infiltrate. Infiltrate may be more extensive than clinically
apparent. Foci of infection may calcify.
Complication - dissemination either by bronchial route or
hematogenous route to involve other organ systems
(renal,cardiac, etc.). Miliary pattern.
Esophageal atresia with or without tracheal fistula
Common developmental disorder involving separation of the
primitive foregut into trachea and esophagus.
May present with gagging or aspiration during feeding. Failure
to allow passage of nasal gastric tube.
X-ray - dilated upper esophagus on PA and lateral films.
Abdomen may be gasless if no fistula. Try not to use
contrast
Complication - pneumonia, failure to thrive. Frequently seen
with other congenital anomalies involving spine,
heart,kidneys, GI tract.
Diaphragmatic hernia
Usually due to embryonic defect in posterolateral portion of
diaphragm. Left hemidiaphragm involved more
than right.
Infants usually asymptomatic at birth but develop progressive
respiratory symptoms especially after feeding.
X-ray - multiple lucencies in one side of chest with
displacement of heart and mediastinum to
opposite side. Abdomen is frequently scaphoid due to lack of bowel.
Complications - respiratory embarrassment due to mass effect.
Lungs may be hypoplastic developmentally.
Surgery to repair defect.
Masses
Masses in chest due to tumor are usually benign, however
neuroblastoma does occur frequently as a posterior mass.
Teratomas or cystic hygromas present in anterior
mediastinum.
While displacement of the trachea and esophagus is not
uncommon, these masses produce mild symptoms
initially.
X-ray- smooth or sharply defined mass displacing the trachea
and extending into lungs. May contain calcium if
teratoma. Hygromas may also be seen extending into neck
in majority of cases.